MUMBAI, India, June 27 -- Intellectual Property India has published a patent application (202517054490 A) filed by Repligen Corporation, Waltham, U.S.A., on June 5, for 'systems and methods for bioproduction process monitoring and control via mid-infrared spectroscopy.'
Inventor(s) include Rowlette, Jeremy Alexander; Hodawadekar, Santosh; Bermudez, Rudolph Matthew; Gantier, Rene; Peyser, James; Salerno, Mark; Lacki, Karol; and West, Jay.
The application for the patent was published on June 27, under issue no. 26/2025.
According to the abstract released by the Intellectual Property India: "Presented herein are methods and systems for monitoring and/or control of production units used at various stages in development and manufacture of biological products. In particular, in certain embodiments, bio-production monitoring and control technologies described herein utilize mid-infrared (mid-IR) analyzers capable of obtaining mid-IR spectral data from aqueous samples in substantially real-time. Technologies described herein may leverage this mid-IR spectral data to measure sample quality metrics, such as protein content, titer, secondary structure, aggregation, etc. as well as viral and/or nucleic acid properties. Sample quality metrics may, accordingly, be measured in substantially real-time and/or on a continuous basis to assess production quality for, e.g., protein therapeutics and gene-therapy agents, and may be used by control systems for adjustment and/or control of process parameters, thereby improving, among other things, product quality."
The patent application was internationally filed on Nov. 15, 2023, under International application No.PCT/US2023/079780.
Disclaimer: Curated by HT Syndication.
