MUMBAI, India, April 20 -- Intellectual Property India has published a patent application (202411074804 A) filed by Ashoka University, Sonipat, Haryana, on Oct. 3, 2024, for 'system to determine stem-like state profiling of tumor samples and a method thereof.'
Inventor(s) include Chowdhury, Debojyoti; Neekhra, Bhavesh; Priyadarshi, Shreyansh; Mukherjee, Swapnanil; Maity, Debashruti; Gupta, Debayan; and Haldar, Shubhasis.
The application for the patent was published on April 17, under issue no. 16/2026.
According to the abstract released by the Intellectual Property India: "The present disclosure provides a system (100) and method (400) for determining stem-like state profiling of tumor samples that utilizes a high-throughput, machine learning-based framework to analyze single-cell and bulk RNA sequencing data. The system (100) includes an input device (102) for receiving RNAseq data, a processing unit (104) equipped with support vector regression-based deconvolution for quantifying cell types, and a support vector machine-based classifier for categorizing cancer stem cells (CSCs) into specific potency states. The system (100) and method (400) improve upon traditional techniques by offering enhanced precision, reduced time and resource requirements, and a robust one-time RNAseq analysis. By integrating reference single-cell RNAseq data and performing rigorous validation, the system (100) generates comprehensive insights into CSC distribution, heterogeneity, and behavior, facilitating personalized therapeutic strategies. This advancement represents a significant leap in cancer research and clinical decision-making."
Disclaimer: Curated by HT Syndication.
