MUMBAI, India, Aug. 22 -- Intellectual Property India has published a patent application (202517070166 A) filed by Eth Zurich, Zurich, on July 23, for 'synthetic transcription factors.'
Inventor(s) include Schweingruber, David; Boschet, Elena; Nelis, Jan; Benenson, Yaakov; and Rechsteiner, Cheyenne.
The application for the patent was published on Aug. 22, under issue no. 34/2025.
According to the abstract released by the Intellectual Property India: "The present invention is generally in the fields of synthetic biology, gene therapy, and cell therapy. The invention relates, inter alia, to a synthetic transcription factor comprising a DNA binding domain derived from a mitochondrial DNA binding protein (e.g. MTERF1) and a transcriptional modulation domain derived from one or more other proteins; a nucleic acid or combination of nucleic acids encoding the inventive synthetic transcription factor; a DNA construct comprising a MTERF1 binding site and a minimal promoter; a system comprising the inventive synthetic transcription factor and the inventive DNA construct; and uses thereof, e.g. medical uses."
The patent application was internationally filed on Dec. 21, 2023, under International application No.PCT/EP2023/087354.
Disclaimer: Curated by HT Syndication.
