MUMBAI, India, April 17 -- Intellectual Property India has published a patent application (202611000058 A) filed by Dr. Vishnu Dev Gupta; Dr. Jyoti Nanda Sharma; Ms. Aditi Srivastava; Dr. Divaker Shukla; Dr. Shalini Sharma; Ms. Ayesha Nisar Shaikh; Ms. Shyalu Gajbhiye; and Ms. Varsha Devi Sahu, Jhunjhunu, Rajasthan, on Jan. 1, for 'synthesis and study of some quinoxaline derivatives as antimicrobial agents.'
Inventor(s) include Dr. Vishnu Dev Gupta; Dr. Jyoti Nanda Sharma; Ms. Aditi Srivastava; Dr. Divaker Shukla; Dr. Shalini Sharma; Ms. Ayesha Nisar Shaikh; Ms. Shyalu Gajbhiye; and Ms. Varsha Devi Sahu.
The application for the patent was published on April 17, under issue no. 16/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to the synthesis and antimicrobial evaluation of novel quinoxaline-based heterocyclic derivatives containing thiazolo and dihydrotriazino moieties. A multistep synthetic strategy involving condensation, chlorination, cyclization, Schiff base formation, and thiocyanate-mediated ring closure was employed to obtain a series of structurally diverse quinoxaline derivatives. The synthesized compounds were characterized by melting point analysis and evaluated for antimicrobial activity using an in vitro agar diffusion method. The compounds were tested against Staphylococcus aureus, Escherichia coli, and Candida albicans. Several derivatives exhibited notable antibacterial and antifungal activity, with one compound showing activity comparable to standard antimicrobial drugs. The disclosed quinoxaline derivatives represent promising lead molecules for the development of new antimicrobial agents to address emerging microbial resistance."
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