MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202521132257 A) filed by Mr. Dinesh L. Bawankar, Wardha, Maharashtra, on Dec. 26, 2025, for 'sustained-release drug delivery microcomposite formulation based on carboxymethylated amorphophallus paeoniifolius starch.'
Inventor(s) include Mr. Dinesh L. Bawankar; and Dr. Ujwalkumar B. Vyas.
The application for the patent was published on Feb. 13, under issue no. 07/2026.
According to the abstract released by the Intellectual Property India: "Sustained-Release Drug Delivery Microcomposite Formulation Based on Carboxymethylated Amorphophallus paeoniifolius Starch. The present invention relates to a sustained-release drug delivery microcomposite formulation and a process for its preparation. The formulation comprises carboxymethylated starch derived from Amorphophallus paeoniifolius as a primary functional polymer, at least one therapeutically active agent entrapped within a cross-linked polymeric matrix, and pharmaceutically acceptable excipients. The polymeric matrix optionally includes polymers selected from alginate, pectin, dextran, and cellulose derivatives, and is ionically cross-linked using multivalent cations to provide controlled and sustained drug release. The invention further provides a process involving deep eutectic solvent-based starch isolation, carboxymethylation of the starch, incorporation of a therapeutically active agent, and bead formation by ionotropic gelation using calcium ions. The optimized microcomposite exhibits controlled and sustained drug release, reduced peak plasma concentration, delayed time to peak concentration, and prolonged mean residence time when compared to conventional immediate-release formulations. Pharmacokinetic evaluations confirm effective in vitro-in vivo correlation and complete drug release within the biological timeframe."
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