Intellectual Property India Publishes Patent Application for 'Surface Modification Of Biodegradable Vascular Stent With Sirolimus Loaded Chitosan/Heparin Nanoparticles To Treat And Prevent Thrombosis Formation In The Vascular System' Filed by Srm Institute Of Science And Technology, Ramapuram Campus; Dr. G. Venkat Kumar; Dr. Puteri Shafinza Abdul-Rahman; and Dr. Gopinath Venkatraman

MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541123062 A) filed by Srm Institute Of Science And Technology, Ramapuram Campus; Dr. G. Venkat Kumar; Dr. Puteri Shafinza Abdul-Rahman; and Dr. Gopinath Venkatraman, Chennai, Tamil Nadu, on Dec. 6, 2025, for 'surface modification of biodegradable vascular stent with sirolimus loaded chitosan/heparin nanoparticles to treat and prevent thrombosis formation in the vascular system.'

Inventor(s) include Dr. G. Venkat Kumar; Dr. Puteri Shafinza Abdul-Rahman; and Dr. Gopinath Venkatraman.

The application for the patent was published on Jan. 2, under issue no. 01/2026.

According to the abstract released by the Intellectual Property India: "The invention relates to a biodegradable vascular stent made of polycaprolactone (PCL) whose surface is modified with sirolimus-loaded chitosan/heparin nanoparticles to prevent thrombosis and enhance hemocompatibility. Nanoparticles are synthesized via ionic gelation and immobilized onto aminolyzed stent surfaces, creating a drug-eluting coating with controlled release capabilities. The modified stent demonstrates improved hydrophilicity, enhanced mechanical stability, excellent blood compatibility, and sustained sirolimus release. These combined features enable the stent to reduce thrombosis risk, minimize restenosis, and eliminate the need for secondary removal procedures."

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