MUMBAI, India, Nov. 14 -- Intellectual Property India has published a patent application (202517095177 A) filed by Pfizer Inc., New York, on Oct. 3, for 'substituted indazole propionic acid derivative compounds and uses thereof as ampk activators.'

Inventor(s) include Bhattacharya, Samit Kumar; Cameron, Kimberly O'Keefe; Conn, Edward Lee; Ebner, David Christopher; Fernando, Dilinie Prasadhini; Filipski, Kevin James; Gerstenberger, Brian Stephen; Huh, Chan Woo; Kung, Daniel Wei-Shung; Lee, Esther Cheng Yin; Mathiowetz, Alan Martin; Mear, Sarah Jane; Obrien, Jessica Gloria Katherine; Smith, Aaron Christopher; and Tu, Meihua Mike.

The application for the patent was published on Nov. 14, under issue no. 46/2025.

According to the abstract released by the Intellectual Property India: "The invention relates to substituted indazole propionic acid derivatives of formula (I), pharmaceutically acceptable salts, tautomers, or pharmaceutically acceptable salts of the tautomers thereof that can activate adenosine 5'-monophosphate- activated protein kinase (AMPK). The invention further relates to pharmaceutical compositions comprising AMPK-activating substituted indazole propionic acid derivatives of formula (I), pharmaceutically acceptable salts, tautomers, or pharmaceutically acceptable salts of the tautomers thereof and at least one pharmaceutically acceptable excipient, and methods of treating a condition comprising administering AMPK-activating substituted indazole propionic acid derivatives of formula (I), pharmaceutically acceptable salts, tautomers, or pharmaceutically acceptable salts of the tautomers thereof."

The patent application was internationally filed on Apr. 03, 2024, under International application No.PCT/IB2024/053239.

Disclaimer: Curated by HT Syndication.