MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202611053028 A) filed by Dr. Neeraj Bhandari; Dr. Tarun Kumar; Dr. Vishal Verma; Ms. Shallu Sharma; Dr. Shabnam Rana; Ms. Gayatri Sharma; and Dr. Dinu Mathew, Pathankot, Punjab, on April 25, for 'standardized detoxification and immunity-enhancing composition from azadirachta indica..'
Inventor(s) include Dr. Neeraj Bhandari; Dr. Tarun Kumar; Dr. Vishal Verma; Ms. Shallu Sharma; Dr. Shabnam Rana; Ms. Gayatri Sharma; Dr. Dinu Mathew; Dr. Neeraj Bhandari; Dr. Tarun Kumar; Dr. Vishal Verma; Ms. Shallu Sharma; Dr. Shabnam Rana; Ms. Gayatri Sharma; and Dr. Dinu Mathew.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a standardized polyherbal composition derived from Azadirachta indica (Neem) extracts, formulated for systemic detoxification and enhancement of innate and adaptive immunity in human subjects. The composition comprises a hydroethanolic extract of neem leaf standardized to not less than 4 percent nimbidin and 2 percent total polyphenols, a supercritical carbon dioxide extract of neem seed kernel standardized to 0.5 to 1.5 percent azadirachtin, present in a weight ratio of 3:1 to 1:1, together with 0.5 to 2 percent piperine as a bioavailability enhancer and pharmaceutically acceptable excipients. The composition is delivered as a 250 to 750 milligram unit oral dose. A process of preparation employing controlled hydroethanolic and supercritical CO2 extractions is also disclosed. The composition demonstrates significant hepatoprotection, induction of Phase II detoxification enzymes, restoration of glutathione, and elevation of CD4+ and CD8+ T-lymphocyte counts in animal and human studies."
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