MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202621043352 A) filed by Mr. Shreyash Diwakar; Rajiv Yadav; Priyanka Shah; Krupa Joshi; Dr Aarti Sachin Zanwar; Bansari G. Antala; Dr Jyoti Saxena; and Maanika Kashyap Menon, Vadodara, Gujarat, on April 5, for 'stability-indicating hptlc method for the estimation of duloxetine in bulk and tablet dosage form.'
Inventor(s) include Mr. Shreyash Diwakar; Rajiv Yadav; Priyanka Shah; Krupa Joshi; Dr Aarti Sachin Zanwar; Bansari G. Antala; Dr Jyoti Saxena; and Maanika Kashyap Menon.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a validated, stability-indicating High-Performance Thin Layer Chromatography (HPTLC) method for the quantitative estimation of Duloxetine in bulk and tablet dosage forms. The method employs pre-coated silica gel 60F254 TLC plates, activated at 60 C, and a mobile phase of methanol: acetonitrile: water (5:4:1, v/v/v). The process includes a chamber saturation time of 45 minutes and a migration distance of 70 mm under ambient conditions. Detection is performed at 212 nm using a deuterium lamp. The method is validated as per ICH guidelines and demonstrates specificity, precision, accuracy, linearity, robustness, and sensitivity. It effectively separates Duloxetine from its degradation products under stress conditions, including acid, base, oxidation, heat, and light, confirming its stability-indicating nature."
Disclaimer: Curated by HT Syndication.
