MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202611027135 A) filed by K. R. Mangalam University, Gurugram, Haryana, on March 8, for 'solid dispersions of aceclofenac and preparation method.'
Inventor(s) include Dr. Khalid Bashir Mir; Dr. Narender Yadav; and Dr. Nisar Ahmed Khan.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a solid dispersion composition of Aceclofenac and a hydrophilic polymeric carrier selected from polyethylene glycol 4000 and polyethylene glycol 6000, and to a process for preparation thereof by a melting method. The drug and carrier are present in weight ratios selected from 1:0.5, 1:1, and 1:1.5. The obtained solid dispersion exhibits improved wettability, enhanced solubility, and increased dissolution rate relative to pure Aceclofenac. In preferred embodiments, polyethylene glycol 6000 at a 1:1.5 drug-to-carrier ratio provides superior performance. Characterization studies indicate reduced crystallinity or amorphization of Aceclofenac in the carrier matrix. The invention is useful for preparing oral pharmaceutical compositions for pain and inflammatory disorders."
Disclaimer: Curated by HT Syndication.
