MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202641050567 A) filed by Jss Academy Of Higher Education & Research, Mysuru, Karnataka, on April 21, for 'silk fibroin nanoparticle for targeted drug delivery.'
Inventor(s) include Sanjay Jayaram; Dr. H V Gangadharappa; Dr. Balamuralidhara V; Keerthiraj K S; Dr. Satish C S; Dr. Madhusudhan K N; and Harshitha R.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a targeted nanotherapeutic system, comprising silk fibroin-based nanoparticles functionalized for receptor-mediated drug delivery. Silk fibroin, a biocompatible and biodegradable protein polymer, enables controlled drug release and high drug-loading capacity. The invention provides a dual drug-loaded nanoparticle system comprising gemcitabine and 5-fluorouracil co-encapsulated within the silk fibroin matrix to achieve anticancer activity through inhibition of DNA synthesis pathways. The nanoparticles are surface-functionalized with a targeting ligand, preferably a peptide such as GE11, enabling selective binding to epidermal growth factor receptors (EGFR) overexpressed on cancer cells."
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