Intellectual Property India Publishes Patent Application for 'Sequential One-Pot Synthesis For Preparing 4-(4-Cyano-2-Methoxyphenyl)-5-Ethoxy-2,8-Dimethyl-1,4- Dihydro-1,6-Naphthyridine-3-Carboxamide' Filed by Bayer Aktiengesellschaft

MUMBAI, India, July 5 -- Intellectual Property India has published a patent application (202517051259 A) filed by Bayer Aktiengesellschaft, Leverkusen, Germany, on May 28, for 'sequential one-pot synthesis for preparing 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4- dihydro-1,6-naphthyridine-3-carboxamide.'

Inventor(s) include Assmann, Jens; Platzek, Johannes; Nowakowski, Marc; and Storch, Dirk.

The application for the patent was published on July 4, under issue no. 27/2025.

According to the abstract released by the Intellectual Property India: "The present invention covers a sequential one-pot synthesis for preparing 4-(4-cyano-2-methoxy-phenyl)- 5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide according to formula (XIII). In particular, in the sequential one-pot synthesis (4R)-4-(4-cyano-2-methoxy-phenyl)-5-ethoxy-2,8-dimethyl- 1,4-dihydro-1,6-naphthyridine-3-carboxamide according to formula ent-(I) is used as starting material to obtain 4-(4-cyano-2-methoxy-phenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3- carboxamide according to formula (XIII) via electrochemical oxidation and electrochemical reduction."

The patent application was internationally filed on Dec. 14, 2023, under International application No.PCT/EP2023/085843.

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