MUMBAI, India, Feb. 6 -- Intellectual Property India has published a patent application (202541123564 A) filed by Saveetha Institute Of Medical And Technical Sciences, Chennai, Tamil Nadu, on Dec. 8, 2025, for 'seal & heal cream a novel combination of wrightia tinctoria, clobetasol propionate 0.05%, 10% urea, and aloe vera for psoriasis.'

Inventor(s) include Keerthana M Ak; Rajesh Kumar S; and Deepak Nallaswamy Veeraiyan.

The application for the patent was published on Feb. 6, under issue no. 06/2026.

According to the abstract released by the Intellectual Property India: "This study, Efficacy of 'Seal&Heal' Cream - A Novel combination of Wrightia Tinctoria, Clobetasol propionate 0.05%, I 0% Urea, and Aloe vera Versus Clobetasol propionate 0.05% monotherapy in the management of psoriasis- A comparative study", evaluates the efficacy of Seal&Heal cream, a novel topical fom1Ulation combining Wrightia Tinctoria, Clobetasol propionate 0.05%, I 0% Urea, and Aloe vera, compared to Clobetasol propionate 0.05% monotherapy in psoriasis management. Psoriasis, a chronic, immunemediated inflammatory skin disorder marked by hyperproliferation and scaling, demands effective multi-targeted treatment. Seal&Heal cream integrates a potent corticosteroid with natural botanical extracts and moisturizing agents to address inflammation, keratinization, and skin batTier dysfunction. The combination aims to enhance therapeutic outcomes by reducing plaque thickness, erythema, scaling, and itch, while improving skin hydration and minimizing steroid-related side effects. Its multi-action ingredients work synergistically to provide sustained relief and enhanced skin repair. This novel formulation offers a promising advancement in topical psoriasis therapy by combining anti-inflammatory, keratolytic, antimicrobial, and wound healing properties, thus improving patient outcomes and quality of life."

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