MUMBAI, India, Oct. 11 -- Intellectual Property India has published a patent application (202421027992 A) filed by Serum Institute Of India Private Limited, Pune, Maharashtra, on April 4, 2024, for 'saccharide coupled microsphere, methods of preparation & applications thereof.'
Inventor(s) include Kadam, Laxmikant Vyankatrao; Gautam, Manish Mahesh; Gairola, Sunil Jagdish Prasad; Murkute, Amol Subhash; and Bhujbal Aniket Sunil.
The application for the patent was published on Oct. 10, under issue no. 41/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to an improved non-covalent (electrostatic) coupling of polysaccharides to microspheres to form couples where structure of saccharides remains unaffected/intact and retaisns epitope confirmation. The stable saccharide coupled microsphere obtained by the method is used for determining the immunogenicity of the immunogenic composition including antigen content determination, identity assay, free saccharide estimation and estimating antibody concentration (IgG) in sera sample. The method is rapid, simple, repeatable, cost effective, scalable, non-toxic to couple microsphere to saccharides. The method results in efficient coupling by selecting correct saccharide size, concentration and pH."
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