Intellectual Property India Publishes Patent Application for 'Protein Complexes For Proximity-Based Labeling Of Intracellular Microenvironments' Filed by The Trustees Of Princeton University

MUMBAI, India, July 25 -- Intellectual Property India has published a patent application (202517061242 A) filed by The Trustees Of Princeton University, Princeton, U.S.A., on June 26, for 'protein complexes for proximity-based labeling of intracellular microenvironments.'

Inventor(s) include Macmillan, David, W. C.; Buksh, Benito; Sakai, Holt; Li, Chun; Knutson, Steven, Douglas; and Wang, Johnny.

The application for the patent was published on July 25, under issue no. 30/2025.

According to the abstract released by the Intellectual Property India: "Protein complexes and associated methods are described herein for proximity-based labeling of various intracellular or intercellular microenvironments. In some embodiments, a protein complex comprises a protein substrate having an ubiquitin E3 ligase associated therewith, wherein a transition metal complex is coupled to the protein substrate. In some embodiments, one or more intermediate molecular species, such as a small molecule and/or protein, reside between the ubiquitin E3 ligase and protein substrate."

The patent application was internationally filed on Nov. 30, 2023, under International application No.PCT/US2023/081832.

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