MUMBAI, India, June 20 -- Intellectual Property India has published a patent application (202321085237 A) filed by Fdc Limited, Maharashtra, on Dec. 13, 2023, for 'process for preparing optically pure arformoterol.'
Inventor(s) include Chandavarkar, Mohan Anand; More, Kishor Ramdas; Sawant, Sudhir Shrirang; Patil, Prashant Bhaskarrao; and Chile, Akshay Rajaram.
The application for the patent was published on June 20, under issue no. 25/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to a novel single-step process for preparing optically pure (RR)-Formoterol (Arformoterol) or its pharmaceutically acceptable salts. The method involves resolving racemic Formoterol (RR, SS) using chiral acids in an organic solvent to yield Arformoterol diastereomeric salt crystals with high enantiomeric and chemical purity. The process is highly cost-effective, scalable, and environmentally friendly, overcoming the limitations of prior art methods. Additionally, the invention provides a complete synthesis pathway for racemic Formoterol, enabling full integration from precursor to final product. The invention is particularly advantageous for industrial production and pharmaceutical applications."
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