MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541122151 A) filed by Vellore Institute Of Technology, Vellore, Tamil Nadu, on Dec. 4, 2025, for 'plant-derived exosomes for cancer treatment.'
Inventor(s) include Dr Ramasamy Tamizhselvi; Ms. Stuti Banerjee; Aparna Eledath Kolasseri; and Dr Sivaraman Jayanthi.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "The present disclosure provides a pharmaceutical composition including plant-derived exosomes isolated from Annona squamosa leaves, the exosomes containing bioactive compounds having anticancer activity, and a pharmaceutically acceptable carrier. The exosomes have a size range of 30-150 nm and contain bioactive compounds including cyclohex-2-enone derivatives, tetradecatriene compounds, cyclohepten-1-one, hexane diisonitrile derivatives, spiro heptane-dione compounds, oxepane, undecadiene derivatives, and hexadecadiene compounds. The bioactive compounds demonstrate binding affinity to p53 tumor suppressor protein with binding energies ranging from 3.1 to -3.5 kcal/mol and modulate cellular pathways including p53 signaling pathways, apoptosis pathways, and MAPK signaling pathways. The exosomes exhibit spherical or saucer-shaped morphology and are isolated through differential centrifugation at speeds ranging from 3,000 g to 10,000 g followed by ultracentrifugation at 150,000 g for 90 minutes."
Disclaimer: Curated by HT Syndication.
