MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202541123996 A) filed by Saveetha Institute Of Medical And Technical Sciences, Chennai, Tamil Nadu, on Dec. 9, 2025, for 'plant-derived exosome-like nanovesicles from lotus stem for biomedical applications.'
Inventor(s) include Dr Neha S; Dr Sankari Malaiappan; and Deepak Nallaswamy Veeraiyan.
The application for the patent was published on Feb. 13, under issue no. 07/2026.
According to the abstract released by the Intellectual Property India: "Exosome-like nanovesicles obtained from plants (PDENs) represent a naturally derived class of nanoscale carriers capable of transporting bioactive molecules for therapeutic and regenerative purposes. They share the core stnictural characteristics of mammalian exosomes yet offer distinct advantages, including renewable sourcing, inherent biocompatibility, absence of zoonotic transmission risks, and the ability to carry both naturally occurring phytoconstituents and externally introduced therapeutic agents. Their versatility makes them suitable for direct biomedical use as well as for acting as delivery vehicles across a wide spectrum of applications. The lotus {Nehunbo nucifera), recognised as the National Flower of India, holds cultural, nutritional, and medicinal relevance. Traditional knowledge and historical usage attribute antioxidant, anti-inflammatory, and restorative benefits to various parts of the plant. The lotus stem, widely consumed as food in certain regions, contains bioactive compounds and represents a safe, plant-based source for PDEN isolation. However, due to high perishability and selective market demand, significant portions of harvested lotus stems remain underutilised beyond culinary or local medicinal use. This makes it a practical and sustainable raw material for high-value biomedical applications. The invention relates to PDENs sourced from lotus stem in a form that preserves their vesicular structure and native molecular profile. These nanovesicles can be deployed for their inherent bioactivity or used as carriers for targeted therapeutic delivery. Potential applications include regenerative medicine, wound healing, periodontal therapy, bone repair, antimicrobial treatment, anti-inflammatory therapy, and advanced drug delivery systems. By integrating the recognised medicinal value and cultural importance of lotus with the principles of green biotechnology and resource optimisation, the invention offers a sustainable and culturally relevant approach to next-generation biomedical innovation."
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