MUMBAI, India, Aug. 22 -- Intellectual Property India has published a patent application (202517074074 A) filed by Spacecraft Seven, Llc, Cranbury, U.S.A., on Aug. 4, for 'plakophilin-2 (pkp2) gene therapy using aav vector.'
Inventor(s) include Herzog, Christopher Dean; Sacramento, Chester Bittencort; Prabhakar, Raj; and Ricks, David.
The application for the patent was published on Aug. 22, under issue no. 34/2025.
According to the abstract released by the Intellectual Property India: "Provided herein is a gene therapy for PKP2 (Plakophilin-2), e.g., using an adeno-associated virus (AAV) vector. The promoter of the vector may be a MHCK7 promoter or a cardiac troponin T (HTNNT2) promoter. The capsid may be an AAV9 or AAVrh.74 or comprise an AAV9 or AAVrh74 capsid protein or a functional variant thereof. Other promoters or capsids may be used. Further provided are methods of treatment, such as by intravenous, intracoronary, intracarotid or intracardiac administration of the rAAV vector, and other compositions and methods."
The patent application was internationally filed on Jan. 05, 2024, under International application No.PCT/US2024/010587.
Disclaimer: Curated by HT Syndication.
