MUMBAI, India, April 17 -- Intellectual Property India has published a patent application (202641022291 A) filed by Christ University, Bengaluru, Karnataka, on Feb 25, for 'photophysically tunable esipt-based organic luminogen for real time monitoring food spoilage and endogenous ammonium in plant systems.'

Inventor(s) include Aakash Venkatesan; Baru Venkata Naga Sahithi; Aatika Nizam; and Vasantha Veerappa Lakshmaiah.

The application for the patent was published on April 17, under issue no. 16/2026.

According to the abstract released by the Intellectual Property India: "The present study relates to a novel orgamc luminogen, (E)-N'-(5-bromo-2- hydroxybenzylidene) nicotinohydrazide (NHMB), which demonstrates exceptional photophysical properties, including dual-state emission, a large Stokes shift, and pHresponsive fluorescence tunability. These features render NHMB particularly suitable for the selective detection and quantification of biogenic amines (BAs) such as ammonia, diethylamine, and triethylamine through ratiometric fluorescence sensing in both solution and solid-state formats. The study provides a sensing platform with low limits of detection (LOD) and quantification (LOQ), enabling highly sensitive analysis of trace-level amines. Furthermore, the luminogen has been successfully incorporated into a hydrogel matrix, allowing for solid-state detection of volatile biogenic amines, particularly those released during food spoilage, thereby offering a practical and user-friendly method for real-time freshness monitoring of perishable products. In addition, the NHMB-based sensing system has demonstrated effective application in plant bioimaging, allowing for the visualization and quantification of endogenous ammonium levels under physiological conditions. This confirms the biocompatibility and adaptability of the system for use in living biological environments. The invention thus provides a versatile and multifunctional ESIPT -based fluorescent probe, offering broad applicability in the fields of agriculture, food safety, and biological diagnostics. The system is cost-effective, easily scalable, and compatible with integration into portable or wearable sensing devices, thereby increasing its viability for commercial and industrial applications."

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