Intellectual Property India Publishes Patent Application for 'Pharmaceutical Composition And Method For Prevention And Treatment Of Hearing Loss' Filed by Pharmazz, Inc.

MUMBAI, India, Jan. 9 -- Intellectual Property India has published a patent application (202517116956 A) filed by Pharmazz, Inc., Willowbrook, U.S.A., on Nov. 25, 2025, for 'pharmaceutical composition and method for prevention and treatment of hearing loss.'

Inventor(s) include Gulati, Kartike.

The application for the patent was published on Jan. 9, under issue no. 02/2026.

According to the abstract released by the Intellectual Property India: "The present invention relates to a composition using an endothelin B receptor agonist, such as sovateltide (N-Succinyl-[Glu9, Ala11,15] endothelin 1, IRL-1620), for increasing proliferation and protecting the existing neuroepithelium of cochlear and vestibular cells located within the otic capsule. The composition is placed transtympanically, via a cochleostomy, or systemically through an intravenous or intramuscular form. A method for treating sensorineural hearing loss and vestibular symptoms caused by degeneration of inner ear cells using a compound that includes endothelin analogs by the mechanism of neuroprotection and neurogenesis of cochleovestibular hair cells and synapses."

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