MUMBAI, India, July 25 -- Intellectual Property India has published a patent application (202421004595 A) filed by Cipla Limited, Maharashtra, on Jan. 23, 2024, for 'parenteral formulations of nimodipine.'
Inventor(s) include Bhadauria, Pradeep; Kaliaperumal, Arunprasath; Rajyaguru, Tushar; Harde, Harshad; and Khairnar, Sandip.
The application for the patent was published on July 25, under issue no. 30/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to stable, sterile, ready-to-use aqueous pharmaceutical formulation comprising nimodipine or its pharmaceutically acceptable salts, and pharmaceutically acceptable excipients. The present invention also relates to a stable, sterile, ready-to-use aqueous pharmaceutical formulation comprising nimodipine containing no more than about 0.41% w/v of nitroso impurity and no more than about 0.41% w/v of di-isopropyl impurity. The formulation is suitable for parenteral administration and is provided in a suitable container. The invention further relates to method of manufacture and sterilization of such formulations and using the formulation for prophylaxis and treatment of ischemic neurological deficits caused by cerebral vasospasm following subarachnoid hemorrhage of aneurysmal origin."
Disclaimer: Curated by HT Syndication.
