MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202641049742 A) filed by Arpita Goswami, Hyderabad, Telangana, on April 19, for 'novel cryoprotectant composition and its application in protein crystal preservation.'

Inventor(s) include Arpita Goswami.

The application for the patent was published on May 1, under issue no. 18/2026.

According to the abstract released by the Intellectual Property India: "The present invention provides a cryoprotectant composition for the preservation of protein crystals, comprising para-hydroxy benzoic acid (PHB) in an aqueous solution. The composition, preferably containing 3.5% (w/v) PHB along with trace amounts of ethanol and dimethyl sulfoxide (DMSO), effectively prevents the formation of ice crystals during cryogenic cooling as demonstrated by X-ray diffraction analysis. The invention maintains high diffraction quality and structural integrity across different protein structural classes. The composition is particularly useful for cryogenic storage, handling, and transport of crystals, while leveraging the antimicrobial properties of PHB for enhanced sample stability."

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