MUMBAI, India, Oct. 11 -- Intellectual Property India has published a patent application (202517061685 A) filed by Malcorp Biodiscoveries Limited, Wellington, New Zealand, on June 27, for 'novel cd20 protein.'

Inventor(s) include Weinkove, Robert; Perret, Rachel; and Rubio-Reyes, Patricia.

The application for the patent was published on Oct. 10, under issue no. 41/2025.

According to the abstract released by the Intellectual Property India: "The present invention is concerned with a human CD20 protein with modifications to one or more intracellular domains sufficient to reduce or abrogate intracellular signalling when attached to or associated with the membrane of the cell such as (e.g.) a T-cell, a natural killer cell, a B-cell, a myeloid cell, a pluripotent stem cell and a haematopoietic stem cell. The present invention further contemplates a nucleic acid encoding a modified human CD20 protein described herein, and to the utility of the modified human CD20 protein as a safety switch in chimeric antigen receptor T-cell therapy or as a selection marker for gene therapies."

The patent application was internationally filed on Nov. 29, 2023, under International application No.PCT/NZ2023/050139.

Disclaimer: Curated by HT Syndication.