MUMBAI, India, Jan. 9 -- Intellectual Property India has published a patent application (202511115866 A) filed by Jawaid Ahmad Khan; and Shabnam, New Delhi, on Nov. 23, 2025, for 'nanosheet-conjugated dsrna foliar spray formulation for control of cotton leaf curl multan virus.'
Inventor(s) include Jawaid Ahmad Khan; Shabnam; and Meryam Sardar.
The application for the patent was published on Jan. 9, under issue no. 02/2026.
According to the abstract released by the Intellectual Property India: "The present method focuses on a dsRNA-based foliar spray designed to protect Nicotiana tabaccum plants from Cotton leaf curl disease (CLCuD). The approach involves the development of a Cotton leaf curl Multan virus (CLCuMuV) V2 gene-derived RNAi construct that expresses specific dsRNA molecules for foliar applications. The V2-derived dsRNA activates the plants RNAi pathway to suppress virus infection by downregulating target, thereby mitigating virus-induced damage and reducing symptoms severity. To enhance the stability and efficacy of dsRNA, the formulation incorporates advanced clay nanosheets as dsRNA carriers, ensuring prolonged delivery of dsRNA to plant cells and providing longer protection compared to naked dsRNA. This innovative strategy offers a sustainable, non-transgenic alternative for managing CLCuD infection, addressing critical challenges in crop protection while minimizing environmental impact."
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