MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541122099 A) filed by Vellore Institute Of Technology, Vellore, Tamil Nadu, on Dec. 4, 2025, for 'nanoparticle-hydrogel composite for sustained l-theanine release.'
Inventor(s) include Perpetual Ansel Chandran; Sai Shraddha; Anushya Selvakumar; Priya Dharshini LC; and Abul Kalam Azad Mandal.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "The present disclosure provides a nanoparticle-hydrogel composite for sustained drug delivery comprising L-theanine as a therapeutic compound, biodegradable polymeric nanoparticles encapsulating the L-theanine, a crosslinked hydrogel matrix, and the nanoparticles being incorporated within the hydrogel matrix to form a composite delivery system. The biodegradable polymeric nanoparticles comprise poly(D,L-lactide-co-glycolide) (PLGA) and the crosslinked hydrogel matrix comprises gelatin crosslinked with polyvinylpyrrolidone (PVP). The crosslinked hydrogel matrix further comprises polyethylene glycol (PEG) and glutaraldehyde as a crosslinking agent. The nanoparticles have an encapsulation efficiency for L-theanine of at least 95%. The composite provides sustained release of L-theanine following Korsmeyer-Peppas release kinetics with a correlation coefficient (R) of at least 0.97. The composite maintains antioxidant activity of the L-theanine of at least 70% as measured by DPPH radical scavenging assay."
Disclaimer: Curated by HT Syndication.
