MUMBAI, India, Oct. 11 -- Intellectual Property India has published a patent application (202517063108 A) filed by Rijksuniversiteit Groningen; and Aarhus Universitet, Groningen, Netherlands, on July 2, for 'nanobody-functionalized biological nanopores and means and methods related thereto.'
Inventor(s) include Maglia, Giovanni; Zhang, Xialin; and Kjems, Jorgen.
The application for the patent was published on Oct. 10, under issue no. 41/2025.
According to the abstract released by the Intellectual Property India: "The invention relates to means and methods for analysis of analytes using nanopore-based sensors, for example, to methods, nanopore systems and devices for the stochastic detection of (label-free) analytes in complex samples, for example the specific detection of a protein biomarker in a bodily sample. Provided is a method for detecting the presence of at least one analyte in a sample using a nanopore system comprising a cis chamber comprising a first conductive liquid medium in liquid communication with a trans chamber comprising a second conductive liquid medium through a modified nanopore, comprising: (a) adding a sample to be analyzed for the presence of an analyte to the cis chamber; (b) optionally applying an electrical potential across the modified nanopore; (c) measuring ionic current passing through the modified nanopore, wherein said modified nanopore is a biological nanopore that is functionalized with a 5 to 50 kDa, preferably 10 to 40 kDa, recognition element (e.g., proteinaceous recognition element) R capable of specifically binding to the analyte."
The patent application was internationally filed on Dec. 01, 2023, under International application No.PCT/NL2023/050633.
Disclaimer: Curated by HT Syndication.
