MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202611001294 A) filed by Guru Kashi University, Bathinda, Punjab, on Jan. 6, for 'multi-pathway modulatory herbal formulation for therapeutic management of breast cancer.'
Inventor(s) include Anupam Sharma; Devinder Kumar Mheshwari; Anil Kumar Sharma; and Gurpreet Singh.
The application for the patent was published on Feb. 13, under issue no. 07/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a new polyherbal composition obtained from Nigella sativa, Murraya koenigii, Azadirachta indica, Syzygium cumini, and Silybum marianum to prevent and/or manage upregulated genes associated with breast cancer. This invention uses a systems biology framework that incorporates compound-target mapping, to build a merged network and, establish hub gene connectivity and enriched pathways influenced by the formulation by using CytoHubba plugin in cytoscape. Application of CytoHubba MCC scoring to the merged network shows that the polyherbal composition interacts with 80 high priority targets which are overlapping genes between herbal formulation and upregulated breast cancer genes and forms the top node in the merged networks. Gene level hub connectivity exhibited high network centrality included EGFR, MET, PIK3R1, PDGFRB, ERBB2, FGFR1, FLT4, KIT, CCND1 and KDR all with high closeness, radiality, and betweenness scores indicating their regulatory roles in the progression of breast cancer. The present invention, therefore, provides a scientifically validated, systems biology-driven, multi-target herbal formulation that offers a new and effective approach to the management of breast cancer."
Disclaimer: Curated by HT Syndication.
