MUMBAI, India, June 20 -- Intellectual Property India has published a patent application (202517033025 A) filed by Nuvig Therapeutics, Inc., Menlo Park, U.S.A., on April 3, for 'modified fc polypeptides with enhanced sialylation.'
Inventor(s) include Conley, Pamela B.; Coffey, Greg P.; and Karbarz, Mark J.
The application for the patent was published on June 20, under issue no. 25/2025.
According to the abstract released by the Intellectual Property India: "The present disclosure relates to compositions containing highly sialylated immunoglobulin Fc polypeptides having an amino acid substitution from phenylalanine to an aliphatic amino acid residue, such as alanine, at amino acid residue 241 of the Fc heavy chain. Further disclosed are methods of manufacturing the highly sialylated Fc polypeptides in a recombinant expression system. Also disclosed are methods of using the disclosed compositions for the treatment of an inflammatory disease or disorder."
The patent application was internationally filed on Sept. 13, 2023, under International application No.PCT/US2023/074097.
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