MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202611000530 A) filed by Dr. Syed Salman Ali; Jaideep Singh Yadav; Md. Rizwanullah; Nishat Saifi; Md. Maruff; and Prawal Kumar Gupta, Greater Noida, Uttar Pradesh, on Jan. 2, for 'method of isorhamnetin isolation from gomphrena serrata and its anti-hyperlipidemic activity.'
Inventor(s) include Dr. Syed Salman Ali; Jaideep Singh Yadav; Md. Rizwanullah; Nishat Saifi; Md. Maruff; and Prawal Kumar Gupta.
The application for the patent was published on Feb. 13, under issue no. 07/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a novel and efficient method for the extraction, isolation, purification, and characterization of isorhamnetin from Gomphrena serrata, a medicinal plant traditionally used for treating metabolic and cardiovascular disorders. The process involves sequential steps of plant material preparation, solvent extraction using polar organic solvents, liquid-liquid partitioning with solvents of varying polarity, and chromatographic purification to obtain high-purity isorhamnetin. Structural confirmation of the isolated compound is achieved through UV-Visible spectroscopy, FT-IR, and NMR analysis. The invention further demonstrates the antihyperlipidemic activity of the purified isorhamnetin in experimentally induced hyperlipidemic animal models, where significant reductions in total cholesterol, triglycerides, LDL, and VLDL levels, along with an increase in HDL levels, were observed. The findings establish Gomphrena serrata as a valuable natural source of isorhamnetin and support its application in developing pharmaceutical and nutraceutical formulations for the effective management of hyperlipidemia and associated cardiovascular diseases."
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