MUMBAI, India, March 14 -- Intellectual Property India has published a patent application (202517120564 A) filed by Cambridge Enterprise Limited; and Transition Bio Limited, Cambridge, U.K., on Dec. 2, 2025, for 'method for quantifying interactions between constituents of a biomolecular system.'
Inventor(s) include Qian, Daoyuan; Arter, Will; Ausserwoger, Hannes; Saar, Kadi Liis; and Knowles, Tuomas.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "According to a first aspect of the disclosure, there is provided a computer implemented method of quantifying interactions between constituents of a bio-molecular system that exhibits phase separation into binary first and second phases in certain conditions, comprising: receiving input data, the input data comprising data describing the bio- molecular system in a plurality of different conditions, differing in at least two parameters, the parameters including the concentration of at least one constituent bio-molecule within the bio-molecular system, wherein for each of the different conditions, the input data comprises data describing the at least two parameters, and the concentration of at least a first of the at least one constituents in the first phase and/or the second phase; determining, based on the input data, a concentration boundary between a first set of data substantially comprising data for which the concentration of the first constituent in the first phase is above a threshold value, and a second set of data substantially comprising data for which the concentration of the first constituent in the first phase is below the threshold value; determining a gradient of the concentration boundary for the concentration of the first constituent with respect to at least one other of the at least two parameters, wherein the gradient corresponds to a portion of the concentration boundary corresponding to a subset of the first set of data and the second set of data that forms part of a third set of data substantially comprising data for conditions in which both the first and second phases are present; and determining, based on the gradient, a stoichiometric parameter quantifying interactions between constituents of the bio-molecular system."
The patent application was internationally filed on May 30, 2024, under International application No.PCT/GB2024/051388.
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