MUMBAI, India, June 6 -- Intellectual Property India has published a patent application (202517048668 A) filed by Tonghua Anrate Biopharmaceutical Co. Ltd., Jilin, China, on May 20, for 'method for preparing high-purity and high-stability protein.'
Inventor(s) include Xiang, Wei; Yue, Zhilei; Dong, Wenwen; and Guan, Tingchen.
The application for the patent was published on June 6, under issue no. 23/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to a method for obtaining high-purity and high-stability recombinant human albumin by adding medium- and long-chain fatty acid ligands and removing a protein having charge heterogeneity by means of anion or/and cation chromatography. The present invention is characterized in that a mixed solution is added to a sample collection solution, the mixed solution is a mixed solution of a fatty acid mixture and poloxamer; the molar ratio of oleic acid to myristic acid to sodium palmitate to sodium stearate to recombinant human albumin is 0.3:0.3:0.3:0.5:1; and truncated albumin and mismatched or modified albumin in recombinant albumin can be effectively removed by means of sequential use of ion exchange chromatography, so that a high-purity and high-stability human albumin sample is obtained."
The patent application was internationally filed on Aug. 28, 2023, under International application No.PCT/CN2023/115220.
Disclaimer: Curated by HT Syndication.
