MUMBAI, India, Jan. 9 -- Intellectual Property India has published a patent application (202511117786 A) filed by Malaviya National Institute Of Technology, Jaipur, Rajasthan, on Nov. 27, 2025, for 'method for iron and water promoted reduction of alkynes to alkenes.'
Inventor(s) include Dr. Raj Kumar Joshi; Manisha; and Lalit Negi.
The application for the patent was published on Jan. 9, under issue no. 02/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to an economical and sustainable methodology for the partial transfer hydrogenation of internal acetylenes to selectively produce E-alkenes. The reaction is catalyzed efficiently under aerobic conditions using iron catalyst, providing high chemo- and stereo-selectivity without the need for pressurized hydrogen gas. In this innovative system, water functions as an environmentally benign hydrogen surrogate, enabling the first demonstration of an iron-water synergistic catalytic process capable of transferring hydrogen to internal acetylenes with controlled stereochemistry. The methodology exhibits excellent functional group tolerance, including aldehyde, nitrile, heteroaromatic, silyl, and ferrocenyl substituents, providing broad applicability in pharmaceutical, fine chemical, and isotope-labeling industries. The protocol is operationally simple, reproducible, and scalable, offering a cost-effective alternative to traditional noble-metal and high-pressure hydrogenation approaches. All the synthesized E-alkenes were characterized via various spectroscopies, such as 1H and 13C-NMR spectroscopy of each molecule."
Disclaimer: Curated by HT Syndication.
