MUMBAI, India, Dec. 13 -- Intellectual Property India has published a patent application (202511086573 A) filed by Deokrishna Kumar Choudhary; Dr. Dube Dheeraj Prakashchand; and Dr. Bikke Ravindra Naik, Mandi, Himachal Pradesh, on Sept. 11, for 'method and system for biosynthesis of zinc oxide nanoparticles and their biomedical application.'

Inventor(s) include Deokrishna Kumar Choudhary; Dr. Dube Dheeraj Prakashchand; and Dr. Bikke Ravindra Naik.

The application for the patent was published on Dec. 12, under issue no. 50/2025.

According to the abstract released by the Intellectual Property India: "The present invention discloses a method and system for biosynthesis of zinc oxide nanoparticles (ZnO NPs) using biological reducing agents derived from plant extracts, microbial supernatants, or enzymatic solutions under precisely controlled operational conditions. The system comprises a bioreactor chamber with inert lining, a programmable biological extract infusion unit, a temperature and pH regulation assembly, a magnetic agitation mechanism, and a nanoparticle recovery and purification subsystem, all integrated with a freeze-drying or spray-drying module. A characterization unit incorporating ultraviolet-visible spectroscopy and dynamic light scattering is embedded for in situ monitoring of nanoparticle nucleation and growth, while a closed-loop feedback technique dynamically regulates infusion rate, temperature, pH, and agitation parameters to ensure reproducibility and uniformity of nanoparticle morphology. The biosynthesized nanoparticles exhibit particle sizes in the range of 10-100 nm with a low polydispersity index and enhanced biocompatibility due to biomolecular capping."

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