MUMBAI, India, Nov. 21 -- Intellectual Property India has published a patent application (202421070661 A) filed by Institute Of Pharmacy, Nirma University; and Gujarat State Biotechnology Mission, Ahmedabad, Gujarat, on Sept. 18, 2024, for '"method and formulation of valacyclovir nanoemulsion through nose-to-brain targeting".'
Inventor(s) include Khushboo Faldu; Vandit Shah; Surabhi Patil; Tejal Mehta; and Jigna Shah.
The application for the patent was published on Nov. 21, under issue no. 47/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to a formulation and a method for preparing a valacyclovir nanoemulsion for nose-to-brain drug delivery, specifically for the treatment and management of Alzheimer's disease. The nanoemulsion formulation comprises valacyclovir as the active pharmaceutical ingredient, isopropyl myristate as the oil phase, Tween 80 as a surfactant, and an aqueous phase comprising dimethyl sulfoxide (DMSO) and double-distilled water. The method of preparation involves a simple and efficient spontaneous emulsification technique, which avoids the use of heat and complex equipment, making the process scalable and cost-effective. This intranasal formulation enhances the bioavailability of valacyclovir in the brain, offers improved therapeutic efficacy, reduces neuroinflammation, and provides a patient-friendly solution for managing Alzheimer's disease."
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