MUMBAI, India, April 17 -- Intellectual Property India has published a patent application (202641043773 A) filed by Nitte, Mangaluru, Karnataka, on April 6, for 'method and composition for enhancing polysaccharide capsule formation in cryptococcus species.'
Inventor(s) include Dr. Vimal Kumar Karnaker; Dr. Asem Ali Ashraf; Dr. Sayantani Nag; and Suhana Nair.
The application for the patent was published on April 17, under issue no. 16/2026.
According to the abstract released by the Intellectual Property India: "Disclosed herein is acapsule-enhancing culture composition (100) for inducing in-vitro enlargement of a polysaccharide capsule in cryptococcus speciesthat comprises a nutrient-rich basal culture medium (102) comprising brain heart infusion (BHI) broth configured to support growth of cryptococcus cells, a nitrogen-containing aqueous carrier medium (104) comprising peptone water;a fermentable carbon source component (106) comprising dextrose configured to promote metabolic activity associated with polysaccharide capsule synthesis;an osmotic and metabolic modulator component (108) comprising mannitol configured to stimulate capsule enlargement;a host-derived biological stimulation component (110) comprising plasma configured to mimic host environmental conditions that promote capsule expansion;a microbial growth-enhancing component (112) comprising a preparation of saccharomyces cerevisiae configured to provide micronutrients and metabolic cofactors supporting polysaccharide production;a urease pathway-influencing component (114) comprising urea configured to interact with urease-linked regulatory pathways of cryptococcus species."
Disclaimer: Curated by HT Syndication.
