MUMBAI, India, April 17 -- Intellectual Property India has published a patent application (202611022962 A) filed by Panipat Institute Of Engineering And Technology, Samalkha, Haryana, on Feb. 26, for 'in silico screening and identification of phytochemical compositions from bertholletia excelsa for anti-acne applications targeting androgen receptor and inflammatory pathways.'
Inventor(s) include Manisha; Gaurav Agarwal; Sonia Narwal; Ritu; and Praveen Nasa.
The application for the patent was published on April 17, under issue no. 16/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a computer-implemented in silico screening and identification method for phytochemical compounds derived from Bertholletia excelsa for anti-acne applications. The invention provides a computational framework for evaluating molecular interactions between plant-derived phytochemicals and acne-associated biological targets, including androgen receptor and inflammatory mediators. The method comprises preparation of target protein structures, generation and optimization of a phytochemical library, validated molecular docking, interaction analysis, and in silico evaluation of drug-likeness and pharmacokinetic properties. The disclosed approach enables efficient identification and prioritization of natural lead compounds with favorable molecular interactions and acceptable pharmacokinetic characteristics, thereby supporting the development of pharmaceutical, cosmeceutical, nutraceutical, and dermatological formulations for acne management while reducing reliance on time-consuming experimental screening methods."
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