MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541123047 A) filed by Vellore Institute Of Technology, Vellore, Tamil Nadu, on Dec. 5, 2025, for 'in-silico method for identifying antidiabetic compounds from medicinal plants.'
Inventor(s) include Dr. Gayathri M; and Ms Ekbote Anvesha Aditya.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "The present disclosure provides a computer-implemented method (100) for identifying antidiabetic compounds from medicinal plants. The method includes selecting medicinal plants with documented antidiabetic properties (102), retrieving three-dimensional structures of phytochemicals from public chemical databases (104), and preparing the phytochemical structures as ligands by optimizing their geometry (106). The method further includes selecting diabetes-related protein targets including dipeptidyl peptidase-4 (DPP-4), alpha-glucosidase, protein tyrosine phosphatase 1B (PTP1B), AMP-activated protein kinase (AMPK), and glucokinase regulatory protein (GKRP) (108), performing molecular docking simulations between the prepared ligands and selected protein targets (110), analyzing molecular docking results to identify ligand-protein pairs with binding affinities below a predetermined threshold (112), conducting ADMET profiling to evaluate absorption, distribution, metabolism, excretion, and toxicity properties (114), performing toxicity prediction analysis (116), and generating a ranked list of antidiabetic compound candidates (118)."
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