MUMBAI, India, Oct. 24 -- Intellectual Property India has published a patent application (202548023098 A) filed by Ablynx Nv, Ghent, Belgium, on March 14, for 'improved immunoglobulin variable domains.'
Inventor(s) include Buyse, Marie-Ange; and Boutton, Carlo.
The application for the patent was published on Oct. 24, under issue no. 43/2025.
According to the abstract released by the Intellectual Property India: "This invention relates to VH domain, in which: (i) the amino acid residue at position 1 12 is one of K or Q; and/or (ii) the amino acid residue at position 89 is T; and/or (iii) the amino acid residue at position 89 is L and the amino acid residue at position 1 10 is one of K or Q; and (iv) in each of cases (i) to (hi), the amino acid at position 1 1 is preferably V; and in which said VH domain contains a C-terminal extension (X)n, in which n is 1 to 10, preferably 1 to 5, such as 1, 2, 3, 4 or 5 (and preferably 1 or 2, such as 1); and each X is an (preferably naturally occurring) amino acid residue that is independently chosen, and preferably independently chosen from the group consisting of alanine (A), glycine (G), valine (V), leucine (L) or isoleucine (I)."
The patent application was internationally filed on May 13, 2015, under International application No.PCT/EP2015/060643.
Disclaimer: Curated by HT Syndication.
