MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541123205 A) filed by G Ashwin Prabhu; Ms. Theevika K; Ms. Ferlinsa J; Ms. Joselin Reina J; and Ms. Poornima Mu, Chennai, Tamil Nadu, on Dec. 6, 2025, for 'identification and screening of antineoplastic secondary metabolites from bacillus licheniformis for cancer treatment.'
Inventor(s) include Ms. Theevika K; Ms. Ferlinsa J; Ms. Joselin Reina J; and Ms. Poornima Mu.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "The present invention provides a computational bioinformatics-based method for identification and screening of antineoplastic compounds from Bacillus licheniformis secondary metabolites. The methodology integrates literature-based strain selection, genome mining using antiSMASH for prediction of biosynthetic gene clusters, collection of secondary metabolite structures from research publications and PubChem database, ADMET evaluation and Lipinski Rule-of-Five filtering, selection of Vascular Endothelial Growth Factor (VEGF) as a cancer-specific therapeutic target, molecular docking to determine binding affinity, and biological activity prediction using PASS. The results identified Notamide F, Indimicin D, and Hopene as lead compounds showing high docking affinity towards VEGF and strong predicted antineoplastic activity. These compounds are proposed as potential candidates for cancer therapy development."
Disclaimer: Curated by HT Syndication.
