MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202641024820 A) filed by Vignan Institute Of Pharmaceutical Technology, Visakhapatnam, Andhra Pradesh, on March 2, for 'hybrid lipid-polymer nanoparticles for sustained release of hydrophobic anticancer agents in hypoxic tumours.'
Inventor(s) include K. Srilekhya; G. Chandrasekhara Rao; Y. Srinivasa Rao; M. Saritha; and P. V. Kamala Kumari.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "The invention presents a groundbreaking hybrid lipid-polymer nanoparticle system engineered for the prolonged delivery of water-repelling cancer-fighting drugs directly into oxygen-deprived tumor areas. This approach tackles the difficulties of treating cancers in low-oxygen environments, where traditional therapies often fail due to quick drug clearance and poor penetration. By merging the strengths of lipid layers for biocompatibility and polymer cores for stability, these nanoparticles ensure a slow, steady release of the drugs over extended periods, boosting their effectiveness against resistant tumor cells while minimizing harm to healthy tissues. The system incorporates smart triggers that respond to the unique conditions of hypoxic tumors, such as acidity or reactive molecules, to optimize drug unleashing. Early tests show enhanced tumor shrinkage and better patient outcomes in models of breast and lung cancers, highlighting its potential as a next-level tool in oncology."
Disclaimer: Curated by HT Syndication.
