MUMBAI, India, Feb. 27 -- Intellectual Property India has published a patent application (202541113007 A) filed by Manipal Academy Of Higher Education, Manipal, Karnataka, on Nov. 18, 2025, for 'hyaluronic acid coated transferosomes hydrogel for methicillin-resistant staphylococcus aureus infected diabetic wounds and method thereof.'
Inventor(s) include Gundawar Ravi; and Roshan Barwa.
The application for the patent was published on Feb. 27, under issue no. 09/2026.
According to the abstract released by the Intellectual Property India: "The invention provides a hyaluronic acid coated transferosomes hydrogel for sustained topical delivery of antibacterial and anti-biofilm agents. The formulation integrates a dual-drug combination of Mupirocin and Baicalein encapsulated within nano-sized transferosomes coated with an amphiphilic hyaluronic acid conjugate. This coating enhances vesicle stability, dermal penetration, and controlled release. The coated transferosomes are embedded within a cross-linked polyacrylic acid hydrogel matrix neutralized with triethanolamine to form a bio adhesive, pH-balanced, and transparent gel. The system achieves prolonged drug release exceeding twenty-four hours, high drug entrapment efficiency, and reduced crystallinity for improved solubility and compatibility. The invention demonstrates superior antimicrobial efficacy against resistant biofilms, enhanced wound-healing activity, and excellent physicochemical stability. The method of preparation involves thin-film hydration, vesicle coating, and hydrogel incorporation, resulting in a uniform, skin-compatible formulation with potential for clinical applications in infection management and topical therapy."
Disclaimer: Curated by HT Syndication.
