MUMBAI, India, April 17 -- Intellectual Property India has published a patent application (202641043218 A) filed by Sr University, Warangal, Telangana, on April 4, for 'fucoidan-capped, moringa oleifera-derived ni-co ferrite nanoparticles with synergistic bioactivity for advanced hyperthermia therapy.'
Inventor(s) include Dr. Mritunjoy Prasad Ghosh; and Ms. Dhriti Kalita.
The application for the patent was published on April 17, under issue no. 16/2026.
According to the abstract released by the Intellectual Property India: "A green and innovative approach is presented for the synthesis of biopolymer-engineered nickel-cobalt spinel ferrite (Ni-Co ferrite) nanoparticles designed for efficient magnetic hyperthermia applications. In this method, a less-explored marine-derived biopolymer, fucoidan, is introduced as a multifunctional capping and stabilizing agent, offering a distinct advantage over commonly used polymers. The synthesis is further supported by the aqueous leaf extract of Moringa oleifera, which plays a dual role as both a natural reducing agent and a source of bioactive compounds. Unlike conventional systems, fucoidan contributes not only to nanoparticle stability through its sulfate-rich structure but also adds biological functionality, including potential anticancer and thermo-sensitizing effects. At the same time, the phytochemicals present in Moringa oleifera assist in forming well-controlled nanoparticles while introducing additional bioactivity at the surface. This combination creates a unique interface between the inorganic core and organic components, improving dispersion, stability, and interaction with biological systems. The synthesized nanoparticles demonstrate effective heat generation when exposed to an alternating magnetic field, reaching the required therapeutic temperature range for hyperthermia. Their performance is evaluated using HeLa cells, where improved cytotoxic effects are observed due to the combined influence of localized heating and bioactive surface components. Overall, this work highlights a fresh and practical strategy that brings together green chemistry and functional biopolymers, offering a more efficient and biologically relevant platform for cancer hyperthermia treatment. Keywords Fucoidan, Moringa oleifera, Nickel-cobalt ferrite nanoparticles, Magnetic hyperthermia, Green synthesis, Cancer therapy."
Disclaimer: Curated by HT Syndication.
