MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202641024819 A) filed by Vignan Institute Of Pharmaceutical Technology, Visakhapatnam, Andhra Pradesh, on March 2, for 'formulation of mucoadhesive buccal films using ai-optimized polymer blends for rapid opioid analgesia.'
Inventor(s) include U. Bhavani; G. Chandrasekhara Rao; Y. Srinivasa Rao; M. Saritha; and K. Srilekhya.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "This invention introduces a groundbreaking approach to pain management through the development of mucoadhesive buccal films that deliver rapid opioid analgesia. By leveraging artificial intelligence (AI) to optimize polymer blends, the formulation achieves superior adhesion to the buccal mucosa, quick dissolution, and controlled release of opioid drugs, such as fentanyl derivatives, directly into the bloodstream. This bypasses the gastrointestinal tract, reducing side effects like nausea and improving bioavailability by up to 40% compared to traditional oral tablets. The AI-driven optimization process analyzes vast datasets on polymer interactions, drug solubility, and mucosal permeability to create custom blends of natural and synthetic polymers, ensuring the films are thin, flexible, and patient-friendly. Key innovations include the integration of bio-compatible enhancers for faster onset of action within 5-10 minutes and enhanced stability for longer shelf life. This technology holds promise for acute pain relief in settings like post-surgical recovery, chronic pain management, and emergency care, offering a non-invasive alternative to injections or pills."
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