MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202641041841 A) filed by K. Santhi Priya; D. Pujitha; D. Nagamani; D. Pavan Venkata Manikanta Promodh; K. Mohan Prudhvi; Ch. Sujitha; A. Preshitha; G. Hema Krishna Kanth; K. N. Ramya Sree; and T. Vineela, Gudlavalleru, Andhra Pradesh, on April 1, for 'formulation and evaluation of betel leaf topical gel using karaya gum and damar gum as natural polymers.'
Inventor(s) include K. Santhi Priya; D. Pujitha; D. Nagamani; D. Pavan Venkata Manikanta Promodh; K. Mohan Prudhvi; Ch. Sujitha; A. Preshitha; G. Hema Krishna Kanth; K. N. Ramya Sree; and T. Vineela.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present study focuses on the formulation and evaluation of a topical gel containing betel leaf (Piper, betle) extract using natural polymers, namely damar gum and karaya gum. The aim was to develop a safe, effective, and patient-friendly topical drug delivery system for localized therapeutic application. Betel leaf is well known for its antimicrobial, anti-inflammatory, and wound-healing properties, making it a suitable candidate for topical formulations. In this study, betel leaf extract was selected and incorporated into gel formulations (F1-F6) prepared with varying concentrations of damar gum and karaya gum, both individually and in combination. The influence of these natural polymers on the physicochemical properties of the gel was systematically investigated. The prepared formulations were evaluated for key parameters including appearance, homogeneity, pH, viscosity, and spreadability. The results indicated that all formulations exhibited acceptable physical characteristics, with variations observed depending on polymer concentration and combination. The optimized formulation demonstrated desirable consistency, good spreadability, suitable pH for skin application, and stable viscosity. Additionally, the optimized gel formulation showed promising antimicrobial activity against selected microbial strains, supporting the therapeutic potential of betel leaf extract in topical applications. Overall, the study concludes that damar gum and karaya gum can be effectively utilized as natural gelling agents in topical gel formulations. The developed betel leaf gel offers a potential natural, safe, and effective alternative for topical drug delivery with improved patient acceptability."
Disclaimer: Curated by HT Syndication.
