MUMBAI, India, Jan. 23 -- Intellectual Property India has published a patent application (202511125225 A) filed by Ms. Amisha Varshney; Dr. Sushil Kumar; Dr. Vandana Arora Sethi; Dr. Lalit Kumar Tyagi; and Mr. Himanshu Gupta, Moradabad, Uttar Pradesh, on Dec. 11, 2025, for 'formulation and development of fast dissolving tablet etodolac by using design of experiments.'
Inventor(s) include Ms. Amisha Varshney; Dr. Sushil Kumar; Dr. Vandana Arora Sethi; Dr. Lalit Kumar Tyagi; and Mr. Himanshu Gupta.
The application for the patent was published on Jan. 23, under issue no. 04/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to fast dissolving tablets of etodolac formulated through direct compression method utilizing superdisintegrants for rapid oral disintegration. The tablets comprise etodolac as active pharmaceutical ingredient combined with croscarmellose sodium and crospovidone as superdisintegrants in varying concentrations of 8%, 12%, and 24%. Design of Experiments methodology using design expert software was employed for systematic optimization of the formulation parameters. The optimized formulation F9 demonstrated superior characteristics with wetting time of 14.85 1.66 seconds, disintegration time of 23.98 1.62 seconds, and drug release of 98.28 2.51% within specified timeframe. The developed fast dissolving tablets eliminate the need for water administration, enhance patient compliance particularly in geriatric and pediatric populations, and provide rapid onset of action through improved bioavailability. The invention addresses the challenges associated with conventional tablet formulations by offering immediate drug release and absorption, thereby improving therapeutic efficacy of etodolac in pain and inflammatory conditions."
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