MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202531102977 A) filed by Vidyasagar University, Midnapore, West Bengal, on Oct. 25, for 'folate receptor-targeted and ph-tunable dextran modified geraniol-protein nano-scaffolds for targeted cancer treatment.'
Inventor(s) include Chaudhuri, Angsuman Das; Mondal, Suman; Mahata, Rumi; Manna, Sounik; Majumder, Anirban; Dey, Surya Kanta; Giri, Dibyendu; Roy, Tamanna; Baral, Rathindra Nath; Roy, Sumita; Saha, Biswajit; and Choudhury, Sujata Maiti.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "The present invention provides nanoscaffold compositions that are targeted to folate receptors and feature pH-tunable properties for the delivery of anticancer agents. These nanoscaffolds are created by modifying dextran with functional groups suitable for conjugation, crosslinking the dextran with a protein backbone to form a stable structure, incorporating or conjugating geraniol within the nanoscaffold framework, and surface-functionalizing the nanoscaffold with folic acid or a folate derivative. The resulting nanoparticles are biocompatible, biodegradable, and capable of sustained drug release under both physiological and acidic conditions. The composition demonstrates enhanced stability, targeted delivery, and reduced systemic toxicity, making them suitable for use in the treatment of colorectal."
Disclaimer: Curated by HT Syndication.
