MUMBAI, India, Aug. 22 -- Intellectual Property India has published a patent application (202517074137 A) filed by Cytiva Bioprocess R&D AB, Uppsala, Sweden, on Aug. 4, for 'elution conditions for protein l affinity chromatography.'

Inventor(s) include Bjorkman, Tomas; Rodrigo, Gustav; and Knutsson, Ulrika.

The application for the patent was published on Aug. 22, under issue no. 34/2025.

According to the abstract released by the Intellectual Property India: "The present invention relates to a method of purifying an antibody or an antibody fragment, adsorbing at least one of the antibody or the antibody fragment onto an affinity separation matrix by contacting a liquid sample with the affinity separation matrix; wherein the affinity matrix is an affinity separation matrix comprises a ligand based on Protein L, or any variation thereof that binds to a ?-light chain of the antibody or antibody fragment, and separating the at least one antibody or antibody fragment from the affinity separation matrix by using an elution buffer, wherein the elution buffer has concentration of 5-50 mM. It equally relates to a method for separation of bispecific antibodies."

The patent application was internationally filed on Jan. 30, 2024, under International application No.PCT/EP2024/052206.

Disclaimer: Curated by HT Syndication.