MUMBAI, India, April 10 -- Intellectual Property India has published a patent application (202411070544 A) filed by Indian Institute Of Technology, Jammu, Jammu & Kashmir, on Sept. 18, 2024, for 'electrochemical device for cardiovascular biomarker detection.'
Inventor(s) include Arun, Ravi Kumar; Kumari, Monika; and Kumar, Natish.
The application for the patent was published on April 10, under issue no. 15/2026.
According to the abstract released by the Intellectual Property India: "An electrochemical device (100) for detecting cardiovascular disease biomarkers comprises a multilayered substrate structure (102) with a protective cover layer. A plasma pad (104) receives separated plasma from from whole blood samples through the sample inlet, while a plasma separation membrane (106) separates plasma from cellular components. A microfluidic channel system (108) directs separated plasma to electrode surfaces of a miniaturized electrode chip (110) comprising working, reference, and counter electrodes. Antibodies specific to myoglobin and cardiac troponin I are immobilized on the working electrode surface through covalent attachment using EDC and NHS crosslinking agents. An electrochemical impedance spectroscopy measurement system (114) detects impedance variations at the electrode-electrolyte interface, while a portable potentiostat provides signal acquisition and processing. The device (100) integrates plasma separation and electrochemical detection on a single platform for simultaneous multiplexed detection of cardiovascular biomarkers, enabling point-of-care cardiovascular disease diagnosis within 5-15 minutes."
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