MUMBAI, India, July 11 -- Intellectual Property India has published a patent application (202511060766 A) filed by Jaypee Institute Of Information Technology, Noida, Uttar Pradesh, on June 25, for 'electrochemical biosensor for detection of mirna-320a and method of preparation thereof.'
Inventor(s) include Utkarsha Srivastava; Prof. Pammi Gauba; and Ashwani Mathur.
The application for the patent was published on July 11, under issue no. 28/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to an electrochemical biosensor designed for the detection of miRNA-320a-5p, a biomarker associated with Polycystic Ovary Syndrome (PCOS). While miRNAs are widely recognized as effective biomarkers for various diseases, no electrochemical biosensor for detecting miRNA-320a-5p currently exists. The present invention provides a novel, point-of-care (POC) diagnostic tool that enables rapid, cost-effective, and highly sensitive detection of miRNA-320a-5p at low concentrations. The biosensor utilizes a gold screen-printed electrode (SPE) functionalized with a thiol-modified anti-sense miRNA-320a-5p probe, allowing for specific hybridization with the target miRNA sequence. The electrochemical response is measured using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), ensuring precise detection. The present invention represents a significant advancement in the early diagnosis of PCOS, facilitating timely medical intervention and disease management. The portable and user-friendly tool further enhances its applicability for clinical and research purposes, making it a valuable tool in personalized medicine."
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